Compounding allows countless active ingredients to be incorporated into customized mouthwashes, gels, troches, etc. For example, to treat periodontal disease, antibiotics can be formulated as a mouthwash, or added to an oral adhesive paste or a plasticized gel that will maintain the contact between the tissue and medication for a prolonged period of time.


Metronidazole 25% in a lipogel-type base provides an efficient treatment of anaerobic infection when applied topically in the periodontal pockets.

Click on the following citations for abstracts/more information:
J Int Acad Periodontol. 2000 Jul;2(3):64-70
Vojnosanit Pregl. 2005 Jul-Aug;62(7-8):565-8
Minerva Stomatol. 2000 Jan-Feb;49(1-2):59-67
J Clin Periodontol. 1992 Oct;19(9 Pt 2):693-7